The Future of Left Atrial Appendage (LAA) Closure

Executive Summary LAA closure is shifting toward next-generation technologies that minimize or eliminate metal implants while improving seal performance and safety. Emerging devices—polymer-based occluders, sealants, foam-fill systems, and hybrid platforms—aim to address limitations of traditional nitinol devices such as peri-device leaks, device-related thrombus, and anatomic incompatibility. These technologies have the potential to simplify procedures, broaden patient eligibility, reduce complications, and reshape the competitive landscape dominated by Watchman and Amulet. This summary provides a concise overview of the major innovation categories and their clinical and industry implications.

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